DDX3Y is likely the key spermatogenic factor in the AZFa region that contributes to human non-obstructive azoospermia
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The latest paper is now available online in Communications Biology. Abstract Non-obstructive azoospermia, the absence of sperm in the ejaculate due to disturbed spermatogenesis, represents the most severe form of male infertility. De novo microdeletions of the Y-chromosomal AZFa region are one of few well-established genetic causes for NOA and are routinely analysed in the […]