Variant PNLDC1, Defective piRNA Processing, and Azoospermia

The latest paper by the GEMINI collaborators is available online in New England Journal of Medicine. Abstract BACKGROUND: P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are short (21 to 35 nucleotides in length) and noncoding and are found almost exclusively in germ cells, where they regulate aberrant expression of transposable elements and postmeiotic gene expression. Critical […]