Variants in GCNA, X-linked germ-cell genome integrity gene, identified in men with primary spermatogenic failure

The latest paper by the GEMINI Consortium is available online in Human Genetics. Abstract Male infertility impacts millions of couples yet, the etiology of primary infertility remains largely unknown. A critical element of successful spermatogenesis is maintenance of genome integrity. Here, we present a genomic study of spermatogenic failure (SPGF). Our initial analysis (n = 176) did […]